فصلنامه نوید نو
پیاپی 61 (زمستان 1394)

Major thalassemia is the most common hereditary anemia in Iran. Diabetes Mellitus (DM) and other endocrine disorders are frequent in thalassemia patients that need regular blood transfusion due to iron overload. This study aims at determining the prevalence of diabetes mellitus in thalassemia patients referring to Ganjavian hospital in Dezful.
This descriptive study was performed on 50 beta-thalassemia patients aged above 5 years old in 2013. For this study, we Examined patient's Fasting blood sugar two times within a month. The serum ferritin levels were measured in these patients. Data were analyzed using SPSS software.
Prevalence of impaired FBS was 15.3% in male and 37.5% in female. Significant correlation was found between the prevalence of DM and desferal taking. In this study the prevalence of DM was 12% and prediabetes was 14%. Prevalence of DM in female patients was significantly higher than that in male patients.
This study shows that patients with Thalassemia major are more susceptible to Diabetes mellitus. In patients with impaired fasting glucose, nutritional counseling should be done to prevent disease progression to diabetes. Also Measuring the FBS in thalassemia patients is recommended in their therapeutic section.

The rapid and extensive development of information and communication technologies has led to difficulties. One of them is too much information retrieval, so we need to select between search engines. The aim of this study was to compare selected Search Engines in retrieving information cleft lip and palate diseases
The current study is an applied research and was carried out using descriptive method. Eight search engines introduced as the most frequently used ones, were the statistical population. Then seven key words of cleft lip and palate diseases were chosen from (Mesh). After data collection, obtained data entered computer and SPSS V.22 and then were analyzed by descriptive method.
results showed that Bing, Yandex and Askjeeves had the highest Precision and they recognized as superior search engines. Bing search engine had the highest false drops and retrieval. Except Gigablast search engine rest of the search engines had the precision above 60%. Bing and Duck Duck search engines had the highest overlap from selected search engines.
based on these findings, it can be concluded that the majority of surveyed and selected search engines had the high retrieval and precision.

Primary erythrocytosis caused defect in progenitor stem cells and this cells became too sensitive to erythropoietin. The most of acquisitive defect is JAK2V617F mutation that observed in 95% of Polycythemia Vera. This mutation was occurred in exon 14 of JAK2 protein. Other mutations accompany with erythrocytosis is JAK2 exon 12 mutations. The number of this mutations is high. In this study we were survey incident four common mutations in exon 12 of JAK2 protein in Mashhad city.
146 patients with Idiopathic Erythrocytosis practiced in cross section study. Patients DNA was screen for F537-K539delinsL, K539L, H538QK539L and N542-E543del mutations by using ARMS-PCR. To detect PCR production has used 2% agarose gel.
Among four mutations of JAK2 exon 12, just observed N542-E543del in two patients (on male, one female). The mean age of patients with N542E543del mutation was 36±19.79 years and patients with N542E543del negative was 44.62±18.88 years.
The result of this study demonstrated that JAK2 exon 12 mutations isn’t a common abnormality in IE patients. To provide more comprehensive report in IE patients, recommended to investigate JAK2 exon12 mutations in large sample size of IE patients or it is suggested DNA sequencing instead of ARMS-PCR.

Cardiovascular Events occur at different ages for different reasons, One of the uncommon causes of sudden cardiac arrest that can be fatal in humans, is Brugada syndrome. The victims are often young men Appearance quite healthy. Its prevalence is high in Southeast Asia.The best treatment method in patients with ECG recognize But without a history of sudden cardiac death, Is that prognosis of clinical variables And ECG in patients with ECG Compatible with Brugada syndrome without previous history of cardiac arrest Effectively be analyzed.
The patient is a young man who in the early morning after waking up from sleep with Syncope and decreased level of consciousness And was brought to hospital emergency. On initial examination, patient had no pulse rate and electrocardiogram showed a straight line And bilateral pupillary dilation And had no reaction to light immediately (CPR) started after about 40 minutes rhythm of the patient was converted to sine and was transferred to the ICU . After transfer to the ICU and perform E.C.G characteristic changes Brugada syndrome was observed. In about a month hospitalization in ICU , and after tracheotomy and insertion(N.G Tube) patient was discharged and transferred to home and through a gastric tube feeding for a long time, he continued, And then with the help of those around him began oral feeding. Currently the patient is not able to mobility and activities and with the help of others continue to vegetative state life.

Multiple sclerosis is the most common progressive neurologic disorder among young adults. This disease leads to lesions regarded to as demylinating plaques which are scattered in the white matter of CNS hence create various neurological problems. The purpose of this study was to assess the effect of one period of selective exercise training on motor function of multiple sclerosis patients.
The present at1392 year and quasi-experimental study used a pretest-posttest design. The subjects with the age of 27-42, expanded disability status scale 1-4 and were purposefully and voluntarily selected and randomly allocated to the experimental(n=8) and control(n=8) groups .exercise training for groups was carried out in 4 weeks, 3sessions per week. In the pre and post timed up and go tests were used to record motor functions. The collected data were then analyzed through Mixed ANOVA at a significance level of P ≤ 0/05.
The results showed that Significant improvements observed in postural sway characteristics of the experimental group .also significant differences observed between post test scores in the experimental and control groups.
The exercise training employed in this study resulted in considerable improvements in static balance in multiple sclerosis.

Aging is one of the critical stages of life and in the near future, a large percentage of Iran's population will be elderly. This period of life is often associated with increased risk of chronic diseases. The aim of this study was to investigate the prevalence of chronic diseases and their impact on quality of life.
Material and A cross-sectional study was conducted on 203 elderly people in Ewaz by multi-stage sampling in 2014. The history of chronic diseases interviews were collected through a check list and face to face interview. Quality of life assessment was carry out using SF-36 questionnaire. Statistical analysis was done using independent sample t-test and chi-square test in SPSS software version 18.
The results showed that 167 (82.26 %) of the elderly have at least one chronic disease and quality of life for people with chronic diseases in all domains was significantly lower than in healthy individuals (p Our findings suggest a high prevalence of chronic diseases in elderly people and its negative impact on their quality of life. Therefore, it is necessary to focus more on elderly people and provide strategies to improve their quality of life.